DNA Chip Gene Analysis System

A Challenge to New Business Regions Fully Utilizing Core Technology

Introduction of the System

The DNA chip “GENE SILICON” for the high-precision measurement of plural items of a gene and analysis system have been developed in response to customer needs in a variety of fields, fully utilizing our core technology.

  • DNA chip “GENE SILICON”

    DNA chip “GENE SILICON”

  • Dedicated analysis system for “GENE SILICON”

    Fluorescent detection device for “GENE SILICON”

Features

1

Our technology enables high-precision measurement

High-precision material and surface treatment technologies unique to accomplish high-accuracy detection
(High S/N achieved through DLC* coating)

In-house technology of Toyo Kohan enables high-precision measurement

2

Several genetic types can be measured simultaneously by one chip

“High reliability” assured through the combination of many genetic polymorphisms

Several genetic types can be measured simultaneously by one chip

3

A substrate that is high in cost competitiveness and is very suitable for production in large quantities

A product that is based on a semiconductor silicon substrate suitable for production in large quantities

A substrate that is high in cost competitiveness and is very suitable for production in large quantities

4

Genes can now be analyzed more easily and simply

Dedicated analysis system featuring compactness and high system operability

Genes can now be analyzed more easily and simply

（*DLC＝Diamond Like Carbon）

[Compliance with Laws and Regulations]
• Manufacturing of medical and pharmaceutical products for extracorporeal diagnosis
(Registration No. 35AZ200013)
• Manufacturing and selling of medical and pharmaceutical products for extracorporeal diagnosis
(Permit No. 13E1X00004)

Measurement Principle

  • DNA Chip

  • Amplified the region of DNA labeled with fluorescent dye
    Genetic types are determined based on fluorescent pattern

How to Use

Protocol

  1. Mixed PCR products and hybridization buffer in the new PCR tubes
  2. Put mixture on the center of the chip cover and covered it to the chip
  3. Incubated at appropriate temperature for 1-2 hours (Hybridization)
  4. After hybridization, Removed the chip cover and washed by washing solution A and B
  5. Analyzed fluorescence pattern by fluorescent detection device (calculate fluorescent intensity for our chip)
  • GENE SILICON
  • Hybridization
  • Detection
  • Result

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